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Author Topic: cardiovascular
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Post cardiovascular
on: September 10, 2014, 12:46
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Fetal erythropoiesis begins in the yolk sac during the third week of intrauterine life and continues until about week 10, when hepatic RBC synthesis begins to predominate (weeks 6 to birth). The spleen contributes from weeks 15 to 30, while the bone marrow begins production of adult Hb at week 22 and continues throughout adulthood. Unlike adult hemoglobin (two alpha, two beta), fetal hemoglobin is composed to two alpha and two gamma globins.

QUESTIONS:
Why does the affinity for oxygen differ between fetal hemoglobin and adult hemoglobin?

For which condition is fetal hemoglobin production preferred, how is such production induced in an adult, and why is it therapeutic?

What are the other types of hemoglobin, and their functions?

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